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Acetaminophen (the generic brand of Tylenol) is one of the most prescribed drugs for pregnant women around the globe to treat fevers and mild pain. It was thought to be safe but now researchers in Denmark have just disrupted the obstetrical community by suggesting that there is an association between taking acetaminophen during pregnancy and hyperactive children who are diagnosed with attention-deficit/hyperactivity disorder.
This is a profound disappointment to most prenatal care providers whose options are limited in what they can prescribe to pregnant women, especially for a fever. It appears that acetaminophen breaks up hormones and according to the researchers, “abnormal hormonal exposures in pregnancy may influence fetal brain development.”
Although the study reports investigating over 62,000 children, a word of caution must be exercised before making the assumption that acetaminophen is not safe for pregnant women. Remember that in this study:
• There was a stronger association between ADHD and acetaminophen if the mother took it for more than one trimester
• The researchers do not know exactly how many pills the pregnant mothers took
• The risks were greater for pregnant women who took large amounts of acetaminophen throughout their pregnancy
• They do not know if pain is associated with an increased risk of developing ADHD
According to the director of the Maternal-Fetal Medicine program at the Cleveland Clinic, it is important to remember that an association of acetaminophen and ADHD is not the same thing as saying acetaminophen causes ADHD and for that reason, he will continue to provide acetaminophen to his pregnant patients advising them to take it in the manner in which it is prescribed.
The take-home message is that most physicians are not going to change their prescribing patterns based on this study. Please consult with your physician or midwife before taking acetaminophen and only take them as prescribed.
Remember, a healthy pregnancy doesn’t just happen; it takes a smart mother who knows what to do. If you like what you read, please like me on Facebook at https://www.facebook.com/SmartMothersGuide or Twitter, yourobgyn@twitter.com